Everything in life arises from faith and the courage to hold on to it. On a journey to find true love, Twist of Fate depicts the story of a superstitious girl named Ada (Cemre Baysel), who believes that she will be cursed for life if she fail to marry her first love. What is going to happen when Ada clings on to her marriage with Rüzgar (İdris Nebi Taşkan) in order not to be doomed, and has to work with her attractive boss, Bora (Aytaç Şaşmaz) who has absolutely no interest in relationship? Despite her self-imposed ill fate, people trying to cut them off, and many other obstacles to surmount, series of events will challenge Ada and Bora individually to learn how to appreciate one another. Fate has twisted, and Cupid hit them both!